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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN1
All Species:
17.27
Human Site:
S376
Identified Species:
29.23
UniProt:
Q16512
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16512
NP_002732.3
942
103932
S376
Y
S
R
S
G
S
L
S
G
R
S
S
L
K
A
Chimpanzee
Pan troglodytes
XP_512443
1169
127241
S603
Y
S
R
S
G
S
L
S
G
R
S
S
L
K
A
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
L444
G
E
L
A
S
E
V
L
A
V
L
K
V
D
N
Dog
Lupus familis
XP_542019
1076
118222
S509
Y
S
R
S
G
S
L
S
G
R
S
S
L
K
V
Cat
Felis silvestris
Mouse
Mus musculus
P70268
946
104392
S379
Y
S
R
S
G
S
L
S
G
R
S
S
L
R
G
Rat
Rattus norvegicus
Q63433
946
104449
S379
Y
N
R
S
G
S
L
S
G
R
S
S
L
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
L431
E
E
L
A
N
E
V
L
A
V
L
K
V
D
N
Chicken
Gallus gallus
XP_422357
1013
114806
G404
R
T
T
K
A
K
A
G
I
S
K
N
L
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689331
948
107057
V389
L
Y
S
R
S
G
S
V
S
G
K
T
P
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
V151
N
L
P
H
R
F
V
V
H
S
Y
K
R
F
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
K224
V
W
K
C
P
G
N
K
A
D
A
V
E
E
L
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
N283
R
L
E
D
F
L
D
N
Q
R
H
G
M
C
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
A342
T
S
T
Y
S
N
S
A
I
Q
S
T
S
A
K
Red Bread Mold
Neurospora crassa
P87253
1142
127954
G430
L
S
F
N
F
I
K
G
A
R
P
Q
G
M
D
Conservation
Percent
Protein Identity:
100
79.3
38.7
83
N.A.
91.6
91.9
N.A.
42.2
57.6
N.A.
66.7
N.A.
29
N.A.
27.8
48.5
Protein Similarity:
100
79.9
52.6
84.3
N.A.
94.7
94.6
N.A.
56.1
72.1
N.A.
79.5
N.A.
42.8
N.A.
43.4
61.7
P-Site Identity:
100
100
0
93.3
N.A.
86.6
86.6
N.A.
0
6.6
N.A.
0
N.A.
0
N.A.
0
6.6
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
93.3
N.A.
20
20
N.A.
6.6
N.A.
6.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
28.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.4
45.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
8
0
8
8
29
0
8
0
0
8
15
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
8
0
0
0
15
8
% D
% Glu:
8
15
8
0
0
15
0
0
0
0
0
0
8
8
0
% E
% Phe:
0
0
8
0
15
8
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
0
0
0
36
15
0
15
36
8
0
8
8
0
15
% G
% His:
0
0
0
8
0
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
15
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
8
8
8
0
0
15
22
0
29
22
% K
% Leu:
15
15
15
0
0
8
36
15
0
0
15
0
43
15
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% M
% Asn:
8
8
0
8
8
8
8
8
0
0
0
8
0
0
15
% N
% Pro:
0
0
8
0
8
0
0
0
0
0
8
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% Q
% Arg:
15
0
36
8
8
0
0
0
0
50
0
0
8
8
0
% R
% Ser:
0
43
8
36
22
36
15
36
8
15
43
36
8
0
0
% S
% Thr:
8
8
15
0
0
0
0
0
0
0
0
15
0
0
8
% T
% Val:
8
0
0
0
0
0
22
15
0
15
0
8
15
0
8
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
36
8
0
8
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _